Ryan Smith is founder of TruDiagnsotic. Ryan received a BA in biochemistry from Transylvania University before heading to medical school in 2013. After passing USMLE Step 1, he decided to leave and open up a pharmacy in the United States that focused on peptide synthesis and formulations for pharmaceutical preparations. That pharmacy, Tailor Made Compounding, became the 4th fastest growing company in healthcare in the US and grew to 80 million in revenue within 3 years. Through this pharmacy work, Ryan saw the value of preventative medicine. Many of the physicians Tailor Made served were treating age as a disease and a primary outcome but needed better tools to measure this process. As a result, Ryan exited Tailor Made in 2020 to create TruDiagnostic.
TruDiagnostic is a CLIA certified lab and health data company which specializes in understanding and reporting insights found through Epigenetic methylation data. Since starting in 2020, TruDiagnostic has created the largest private epigenetic database in the world with over 15,000 patients tested on the EPIC850k array. From this dataset, they have created many new algorithms to interpret methylation data including algorithms to predict inflammatory markers, disease diagnosis, telomere length, aging pace, immune cell subsets, cellular replication, and more. TruDiagnostics has also led research in the field with over 30+ clinical trials investigating the best ways to reverse these markers through diet, lifestyle, and prescription interventions. Currently, TruDiagnostic is working with collaborators from Duke, Harvard, Yale, UCSF, Ohio St. and more to uncover new insights from the methylome. TruDiagnostic is also the only commercial company on the market to offer 2nd or 3rd generation aging algorithms which have shown to be more predictive and precise than 1st generation aging clocks.
In addition to his work with pharmaceuticals, Ryan also consults with international pharmacies and has set up pharmacies in Thailand and Mexico. In addition, Ryan has developed novel supplements and cosmetic formulations with multiple 100M supplement brands and consults with clinics in the cash pay wellness space.